Carbamic acid, [(2S)-2-aminopropyl]-, 1,1-dimethylethyl ester - Names and Identifiers
Name | Carbamic acid, [(2S)-2-aminopropyl]-, 1,1-dimethylethyl ester
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Synonyms | (S)-tert-butyl 2-aminopropylcarbamate tert-Butyl ((2S)-2-aminopropyl)carbamate tert-Butyl N-[(2S)-2-aMinopropyl]carbaMate (S)-1-N-Boc-Propane-1,2-diaMine hydrochloride ((S)-2-Aminopropyl)carbamic acid tert-butyl ester N-((S)-2-Aminopropyl)carbamic acid tert-butyl ester CarbaMic acid, [(2S)-2-aMinopropyl]-, 1,1-diMethylethyl ester Carbamic acid, [(2S)-2-aminopropyl]-, 1,1-dimethylethyl ester Carbamic acid, [(2S)-2-aminopropyl]-, 1,1-dimethylethyl ester (9CI)
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CAS | 121103-15-9
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Carbamic acid, [(2S)-2-aminopropyl]-, 1,1-dimethylethyl ester - Physico-chemical Properties
Molecular Formula | C8H18N2O2
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Molar Mass | 174.24 |
Density | 0.984 |
Boling Point | 263.7±23.0 °C(Predicted) |
pKa | 12.51±0.46(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Carbamic acid, [(2S)-2-aminopropyl]-, 1,1-dimethylethyl ester - Introduction
tert-Butyl (2S)-2-aminopropyl) carbamate, also known as tert-butyl N-(2-aminopropyl) carbamate, is an organic compound. Its chemical formula is C8H18N2O2 and its molecular weight is 174.24g/mol.
Nature:
(2S)-2-aminopropyl) carbamic acid tert-butyl ester is a colorless to light yellow liquid, water-soluble and soluble in common organic solvents.
Use:
(2S)-2-aminopropyl) carbamic acid tert-butyl ester is mainly used as a pharmaceutical intermediate, which plays the role of connecting and modifying the chemical structure in the synthesis of drugs. It can be used to synthesize anti-cancer drugs, anti-AIDS drugs, analgesic drugs, etc.
Preparation Method:
(2S)-2-aminopropyl) carbamic acid tert-butyl ester can be prepared by many methods. The common method is to react tert-butyl alcohol and aminoethanol under acid catalysis to form tert-butyl N-(2-aminopropyl) carbamate. The reaction is usually carried out under an inert atmosphere and the reaction temperature is usually from room temperature to 50°C.
Safety Information:
(2S)-2-aminopropyl) carbamic acid tert-butyl ester is relatively stable under normal operating conditions, but it is necessary to avoid high temperature and strong oxidant contact. During operation, it is recommended to wear protective gloves and goggles to ensure adequate ventilation.
The information provided here is for reference only. Please read the relevant safety instructions and operating procedures carefully before use to ensure safe use.
Last Update:2024-04-09 15:17:51